An independent clinical research site · Guaynabo, Puerto Rico
Advancing clinical research across diverse therapeutic areas.
Conducting industry-sponsored clinical trials to advance medical research and improve patient care. ISIS Clinical Research Center P.S.C. runs Phase II–III studies in Guaynabo, Puerto Rico, with an experienced research team and access to an established clinical patient population.
About a minute · Medical records may be requested later
- No cost for study-related care
- Insurance not required
- English & Spanish
- San Juan metropolitan area
- IRB-approved protocols
How can we help you today?
One research center. Two ways to work with us.
I'm a patient or caregiver
Explore study opportunities for your condition, receive study-related care at no cost and help researchers evaluate new treatments.
- No cost for study-related care
- Health insurance is not required
- You can withdraw at any time
I'm a sponsor or CRO
An independent Phase II–III site in Guaynabo, Puerto Rico, conducting industry-sponsored trials with access to an established clinical patient population.
- Phase II–III across diverse therapeutic areas
- Established practice, referrals & outreach
- On-site liver elastography, ECG & sample processing
Therapeutic areas
Research across diverse therapeutic areas
Studies are conducted by an experienced investigator team, supported by an established endocrinology and obesity medicine practice.
Study opportunities
Explore study opportunities
Study availability varies throughout the year. Contact our research team to learn about current opportunities and determine whether a study may be right for you.
Study availability varies throughout the year. You can join our interest registry for future studies below.
Our research team will contact you when a future study may be a fit. Joining the registry does not enroll you in a study.
Why participate
Study-related care, in your language
Eligible participants may receive study-related visits, tests, and study medication at no cost, as described in the study documents. Depending on the study, participants may receive an investigational treatment, an approved comparator, or placebo. Participation involves risks, and medical benefit is not guaranteed.
A welcoming environment.
Personalized attention. A dedicated team throughout your research journey.
Investigational treatments
Depending on the study, you may receive an investigational treatment, an approved comparator, or placebo.
Study-related care at no cost
Study-related visits, tests, and study medication, as described in the study documents.
Time & travel support
Many studies offer stipends and travel reimbursement.
Help your community
Help researchers evaluate the safety and efficacy of investigational treatments.
Our story
Clinical research experience since 2018
Our clinical research experience dates to 2018. Incorporated in 2023 as ISIS Clinical Research Center P.S.C., our independent clinical research site conducts Phase II–III clinical trials in Puerto Rico in collaboration with pharmaceutical sponsors and contract research organizations.
Paola Mansilla-Letelier, MD, DABOM
Dr. Mansilla-Letelier is an endocrinologist and Diplomate of the American Board of Obesity Medicine. She founded ISIS Clinical Research Center P.S.C. and is Founder and President of the Sociedad de Obesidad y Síndromes Asociados in Puerto Rico. Her work connects clinical care, research, and physician education.
- Founder & Chief Executive Officer · Principal Investigator
- Endocrinologist · Obesity Medicine Specialist
- Founder & President, Sociedad de Obesidad y Síndromes Asociados
What to expect
How participation works
After an initial conversation with our team, you will have the opportunity to review the informed consent document and ask questions. The consent process is completed before any study-specific research procedures are performed. Participation depends on the study's eligibility criteria.
- Initial inquiryShare your contact details online or by phone. A brief preliminary pre-screening may follow.
- Talk with a research coordinatorWe explain the study, answer your questions and review the next steps with you.
- Informed consentReview the consent document, ask questions and decide. Participation is always voluntary.
- Study-specific screeningScreening procedures take place only after the consent process is completed.
- Enrollment, if eligibleParticipation depends on the study's eligibility criteria.
Why Puerto Rico · Why ISIS
A U.S. research site with established patient access
Phase II–III clinical trials in Guaynabo, Puerto Rico, within the San Juan metropolitan area, supported by an experienced investigator team and bilingual research operations.
Established patient access
Access to Hispanic and Puerto Rican patient populations, supported by established clinical relationships and community referral networks.
Fully bilingual
English and Spanish, from sponsor calls to informed consent.
FDA, IRB & GCP
Clinical trials conducted in accordance with applicable FDA regulations, Institutional Review Board (IRB) requirements and Good Clinical Practice.
Experienced investigator team
Principal investigators and sub-investigators across specialties, led by an endocrinologist and obesity medicine specialist.
Questions & answers
Everything you want to know before joining
Still have questions?
Talk to a coordinator in English or Spanish.
Is participating in a clinical trial safe?
Every study is reviewed and approved by an Institutional Review Board (IRB) and conducted in accordance with applicable FDA regulations and Good Clinical Practice. Your safety is monitored throughout the study.
Does completing the online form mean I qualify for a study?
No. The online form is a contact request, not an eligibility assessment. Eligibility can only be determined by the study team after informed consent and study-specific screening procedures.
Do I need health insurance?
No. Eligible participants may receive study-related visits, tests, and study medication at no cost, as described in the study documents.
Will I receive the investigational treatment?
Depending on the study, participants may receive an investigational treatment, an approved comparator, or placebo. Participation involves risks, and medical benefit is not guaranteed.
Will I be paid for participating?
Compensation varies by study. Many protocols offer stipends for your time and travel. Your coordinator explains it before you decide.
Can I leave a study after I join?
Yes. Participation is 100% voluntary and you can withdraw at any time, for any reason, without affecting your regular care.
Are services available in Spanish?
Yes. Our team is fully bilingual. Consent documents and materials are available in English and Spanish.
Will my regular doctor know about my participation?
Only with your written permission. With it, we can share study progress with your primary care physician.
Ready to take the first step?
Send us a short inquiry or call us at (939) 577-4280. Our research team will contact you as soon as possible.